Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.71 |
| ▸ | FLT1 | P17948 | 6/20 | 0.60 |
| ▸ | FLT4 | P35916 | 6/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884018 | 0.83 | KDR (1.00) | KDRFLT1FLT4 | |
| SCHEMBL3885345 | 0.82 | KDR (0.76) | KDRFLT1FLT4 | |
| SCHEMBL27761181 | 0.82 | KDR (0.78) | KDRFLT1FLT4 | |
| SCHEMBL3894150 | 0.81 | KDR (0.82) | KDRFLT1FLT4 | |
| SCHEMBL3885228 | 0.80 | KDR (1.00) | KDRFLT1FLT4 | |
| SCHEMBL27761173 | 0.79 | KDR (0.73) | KDRFLT1FLT4 | |
| SCHEMBL2564102 | 0.77 | KDR (1.00) | KDRFLT1FLT4 | |
| SCHEMBL3888183 | 0.77 | KDR (1.00) | KDRFLT1FLT4 | |
| SCHEMBL3889036 | 0.76 | KDR (1.00) | KDRFLT1FLT4 | |
| SCHEMBL5483380 | 0.75 | KDR (0.83) | KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437577-A | Combination therapy for diseases involving angiogenesis | BAUSCH & LOMB (US) | 2009-05-20 | — | — | CN | disclosed |