SCHEMBL27740765

SCHEMBL27740765

CNCC(O)C(c1ccccc1OC)n1ccc2ccccc21

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 20/20 0.74
SLC6A4 P31645 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4087372 0.88 SLC6A2 (0.69) SLC6A2SLC6A4
SCHEMBL4077141 0.88 SLC6A2 (0.69) SLC6A2SLC6A4
SCHEMBL4087419 0.88 SLC6A2 (0.69) SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL4086940 0.87 SLC6A2 (0.67) SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL4081317 0.87 SLC6A2 (0.67) SLC6A2SLC6A4
Hydrochloric Acid SCHEMBL5731792 0.87 SLC6A2 (0.67) SLC6A2SLC6A4
SCHEMBL4091255 0.85 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL4085809 0.85 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL4081780 0.85 SLC6A2 (1.00) SLC6A2SLC6A4
SCHEMBL4086767 0.85 SLC6A2 (1.00) SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101309904-A 1- (1H-indol-1-yl) -3- (methylamino) -1-phenylpropan-2-ol derivatives and related compounds as monoamine reuptake modulators for the treatment of vasomotor symptoms (VMS) WYETH CORP (US) 2008-11-19 CN disclosed