Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28281346 | 0.74 | MAPT (0.44) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27668573 | 0.71 | MAPT (0.41) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL9198685 | 0.71 | MAPT (0.42) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27390431 | 0.71 | MAPT (0.46) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27741901 | 0.71 | NPC1 (0.40) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27534182 | 0.70 | BCHE (0.48) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL28150514 | 0.68 | NPC1 (0.43) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27762380 | 0.68 | MAPT (0.42) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL27968733 | 0.68 | MAPT (0.45) | MAPTBCHENPC1RAB9ACYP3A4 | |
| SCHEMBL2768944 | 0.65 | MAPT (0.45) | MAPTBCHENPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448551-A | Use of chalcones for the treatment of viral disorders | JOHNSON & JOHNSON CONSUMER (US) | 2009-06-03 | — | — | CN | disclosed |