Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAK | O14976 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21348746 | 0.86 | — | — | |
| SCHEMBL1145890 | 0.81 | KDM4E (0.42) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL15491230 | 0.79 | HDAC8 (0.33) | ACACBFFAR1EGLN2GRM5HRH3 | |
| SCHEMBL19113961 | 0.76 | FFAR1 (0.38) | ACACBFFAR1GRM5HRH3HDAC8 | |
| SCHEMBL22031755 | 0.75 | FFAR1 (0.33) | FFAR1EGLN2HDAC8 | |
| SCHEMBL22387470 | 0.75 | FFAR1 (0.33) | FFAR1EGLN2HDAC8 | |
| SCHEMBL22031495 | 0.75 | CCR1 (0.35) | FFAR1EGLN2HDAC8 | |
| SCHEMBL3010045 | 0.75 | FFAR1 (0.37) | PIK3CAPI4KAPI4KBACACBFFAR1 | |
| SCHEMBL31098105 | 0.75 | CCR1 (0.35) | FFAR1EGLN2HDAC8 | |
| SCHEMBL503728 | 0.75 | CYP1A2 (0.34) | FFAR1EGLN2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101668767-A | Pyridine derivatives substituted with heterocyclic ring and phosphonoamino group and antifungal agent containing the same | EISAI R&D MAN CO LTD | 2010-03-10 | — | — | CN | disclosed |
| CN-101300250-A | Heterocyclic substituted pyridine derivative and antifungal agent containing the same | EISAI R&D MAN CO LTD (JP) | 2008-11-05 | — | — | CN | disclosed |