Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607580 | 0.80 | AHR (0.48) | BACE1AHRKEAP1PDPK1HTR2A | |
| SCHEMBL3150146 | 0.77 | AHR (0.46) | AHRKEAP1PDPK1HTR2AHTR2C | |
| SCHEMBL28755886 | 0.77 | AHR (0.46) | BACE1AHRKEAP1PDPK1HTR2A | |
| SCHEMBL27778491 | 0.76 | AHR (0.35) | AHRHTR2AHTR2C | |
| Ethoxycarbonyl Group SCHEMBL28109545 | 0.75 | BCHE (0.38) | BACE1KEAP1PDPK1HTR2AHTR2C | |
| SCHEMBL3535407 | 0.75 | AHR (0.43) | AHRKEAP1HTR2AHTR2CBCHE | |
| SCHEMBL593512 | 0.74 | AHR (0.50) | BACE1AHRKEAP1PDPK1BCHE | |
| SCHEMBL14256041 | 0.73 | AHR (0.42) | AHRKEAP1HTR2AHTR2CBCHE | |
| SCHEMBL27743081 | 0.73 | DAO (0.43) | AHRBCHE | |
| Tert-Butyl Formate SCHEMBL27584077 | 0.73 | HTR2A (0.40) | BACE1AHRHTR2AHTR2CBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101437519-A | Indazole compounds | ABBOTT LAB (US) | 2009-05-20 | — | — | CN | disclosed |