Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL492177 | 0.86 | TP53 (0.36) | HRH4HTR3AKDM4EMEN1ALDH1A1 | |
| SCHEMBL492126 | 0.83 | CHRNA7 (0.46) | HTR3A | |
| SCHEMBL492099 | 0.83 | CHRNA7 (0.46) | HTR3A | |
| SCHEMBL492211 | 0.76 | JAK3 (0.33) | ALDH1A1IP6K1IP6K3 | |
| SCHEMBL491967 | 0.76 | SOS1 (0.34) | KDM4EMEN1ALDH1A1KMT2AGRM4 | |
| SCHEMBL492693 | 0.76 | IP6K1 (0.46) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL27723455 | 0.75 | — | — | |
| SCHEMBL492722 | 0.74 | ABL1 (0.42) | — | |
| SCHEMBL492891 | 0.74 | ABL1 (0.42) | — | |
| SCHEMBL492151 | 0.72 | HDAC4 (0.45) | HRH4GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101312968-A | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof | MEMORY PHARM CORP (US) | 2008-11-26 | — | — | CN | disclosed |