Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 11/20 | 0.63 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.63 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.63 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionamide SCHEMBL27724168 | 0.94 | MAPK13 (0.66) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| Acetamide SCHEMBL27744839 | 0.91 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769642 | 0.91 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770167 | 0.91 | MAPK13 (0.74) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL27724034 | 0.88 | MAPK13 (0.64) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769239 | 0.86 | MAPK13 (0.73) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| Dimethylformamide SCHEMBL28776507 | 0.85 | MAPK13 (0.66) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5771432 | 0.83 | MAPK13 (0.66) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5773967 | 0.83 | MAPK13 (0.65) | MAPK13MAPK12MAPK11MAPK14CSNK1A1 | |
| SCHEMBL28773097 | 0.82 | MAPK13 (0.67) | MAPK13MAPK12MAPK11MAPK14SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100443481-C | Imidazolyl-cyclic acetals | RHONE POULENC RORER LTD (GB) | 2008-12-17 | — | — | CN | claimed |
| CN-100443481-C | Imidazolyl-cyclic acetals | RHONE POULENC RORER LTD (GB) | 2008-12-17 | — | — | CN | disclosed |