Uric Acid

Uric Acid

SCHEMBL27744864

N#CN.O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1

nearest known ligand 0.73

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.73
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
BRPF1 P55201 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TYMP P19971 5/20 0.33
IDO1 P14902 4/20 0.33
DPYD Q12882 1/20 0.33
GSK3B P49841 1/20 0.33
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uric Acid SCHEMBL27548112 0.88 GDA (0.76) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL28328546 0.88 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL16213309 0.88 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL10631703 0.88 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL27432318 0.86 GDA (0.73) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL28323281 0.86 GDA (0.73) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL27648863 0.86 GDA (0.73) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL28124016 0.86 GDA (0.73) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL924097 0.85 GDA (0.89) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL3417988 0.85 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105385485-A Grease composition special for automotive plastic parts and preparation method thereof CHINA PETROLEUM & CHEM CORP 2016-03-09 CN claimed
CN-105385485-A Grease composition special for automotive plastic parts and preparation method thereof CHINA PETROLEUM & CHEM CORP 2016-03-09 CN disclosed
CN-104892974-A Environment-friendly inorganic flame retardant UNIV ZHEJIANG OCEAN 2015-09-09 CN disclosed
CN-101462023-B Method for improving the hydrolysis of a reducing agent in a waste gas treatment system MAN NUTZFAHRZEUGE AG 2013-05-29 CN disclosed
CN-101462023-A Method for improving the hydrolysis of a reducing agent in a waste gas treatment system MAN NUTZFAHRZEUGE AG (DE) 2009-06-24 CN disclosed