Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.66 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.54 |
| ▸ | PRKACA | P17612 | 7/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335365 | 0.89 | MAPK14 (0.76) | MAPK14MAPT | |
| SCHEMBL1877952 | 0.89 | MAPK14 (0.68) | MAPK14ROCK1PRKACACYP3A4USP2 | |
| SCHEMBL4332791 | 0.88 | MAPK14 (0.66) | MAPK14ROCK1 | |
| SCHEMBL4335680 | 0.87 | MAPK14 (0.70) | MAPK14KMT2AHSD17B10WNT3A | |
| SCHEMBL4335472 | 0.86 | MAPK14 (0.69) | MAPK14USP2MAPTKMT2ANPSR1 | |
| SCHEMBL4332734 | 0.85 | MAPK14 (0.87) | MAPK14ROCK1PRKACAMAPTHSD17B10 | |
| SCHEMBL4338156 | 0.85 | MAPK14 (0.65) | MAPK14ROCK1PRKACACYP3A4 | |
| SCHEMBL4341338 | 0.85 | MAPK14 (0.70) | MAPK14ROCK1PRKACACYP3A4USP2 | |
| SCHEMBL27765846 | 0.85 | MAPK14 (0.70) | MAPK14ROCK1PRKACAHSD17B10WNT3A | |
| SCHEMBL4341525 | 0.85 | MAPK14 (0.67) | MAPK14ROCK1PRKACAUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472921-A | Pyridylisoxazole derivative | ASKA PHARM CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |