Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 11/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767688 | 0.92 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL27724640 | 0.91 | MAPK13 (0.55) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5770025 | 0.90 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769271 | 0.90 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL27744982 | 0.90 | MAPK13 (0.56) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769809 | 0.88 | MAPK14 (0.59) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5772144 | 0.87 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14SOAT1 | |
| SCHEMBL5769277 | 0.86 | MAPK14 (0.59) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5771522 | 0.86 | MAPK14 (0.58) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL5767833 | 0.86 | MAPK14 (0.58) | MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100443481-C | Imidazolyl-cyclic acetals | RHONE POULENC RORER LTD (GB) | 2008-12-17 | — | — | CN | disclosed |