Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | SNCA | P37840 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774588 | 1.00 | CYP19A1 (0.60) | CYP19A1BACE1SNCAAPPRAB9A | |
| SCHEMBL11307656 | 0.93 | CYP19A1 (0.65) | CYP19A1BACE1RAB9AMAPTNPC1 | |
| SCHEMBL11307663 | 0.93 | CYP19A1 (0.65) | CYP19A1BACE1RAB9AMAPTNPC1 | |
| SCHEMBL29809086 | 0.93 | CYP19A1 (0.65) | CYP19A1BACE1RAB9AMAPTNPC1 | |
| SCHEMBL11299294 | 0.89 | CYP19A1 (0.62) | CYP19A1SNCAAPPRAB9AMAPT | |
| SCHEMBL29594574 | 0.89 | MAPT (0.66) | CYP19A1BACE1RAB9AMAPTNPC1 | |
| SCHEMBL10940074 | 0.89 | CYP19A1 (0.62) | CYP19A1SNCAAPPRAB9AMAPT | |
| SCHEMBL5442818 | 0.89 | MAPT (0.66) | CYP19A1BACE1RAB9AMAPTNPC1 | |
| SCHEMBL1578978 | 0.89 | MAPT (0.66) | CYP19A1BACE1RAB9AMAPTNPC1 | |
| SCHEMBL1578983 | 0.89 | MAPT (0.66) | CYP19A1BACE1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100302927-A1 | OPTICAL DATA STORAGE MEDIUM AND METHODS FOR USING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2010-12-02 | — | — | US | disclosed |
| US-4332739-A | Process for the manufacture of aromatic isocyanates | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1982-06-01 | — | — | US | disclosed |