⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28514392 | 0.80 | — | — | |
| SCHEMBL5742302 | 0.80 | — | — | |
| SCHEMBL3740631 | 0.74 | — | — | |
| SCHEMBL28327359 | 0.68 | — | — | |
| SCHEMBL1967447 | 0.68 | — | — | |
| SCHEMBL28966116 | 0.67 | — | — | |
| SCHEMBL28966118 | 0.67 | — | — | |
| SCHEMBL4652548 | 0.66 | — | — | |
| SCHEMBL547381 | 0.66 | — | — | |
| Acetic Acid SCHEMBL10353287 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103649053-B | Aminomethyl quinolone compounds | 霍夫曼-拉罗奇有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-105120869-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-12-02 | — | — | CN | disclosed |
| CN-105101996-A | Treatment of ocular disorders | KADMON CORP LLC | 2015-11-25 | — | — | CN | disclosed |
| CN-105001302-A | Cyclic peptide inhibitors of hepatitis C virus replication | INTERMUNE INC | 2015-10-28 | — | — | CN | disclosed |
| CN-102741270-B | Cyclic peptide inhibitors of hepatitis C virus replication | INTERMUNE INC | 2015-07-22 | — | — | CN | disclosed |
| CN-103649053-A | Aminomethyl quinolone compounds | HOFFMANN LA ROCHE | 2014-03-19 | — | — | CN | disclosed |
| CN-102741270-A | Cyclic peptide inhibitors of hepatitis c virus replication | INTERMUNE INC | 2012-10-17 | — | — | CN | disclosed |
| CN-101336232-B | 3' -alkoxy-spirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG | 2012-08-29 | — | — | CN | disclosed |
| CN-101801933-A | quinolone derivative | ASTELLAS PHARMA INC | 2010-08-11 | — | — | CN | disclosed |
| CN-101336232-A | 3' -alkoxy-spirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2008-12-31 | — | — | CN | disclosed |