⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1359728 | 0.81 | HIF1A (0.46) | — | |
| SCHEMBL8608196 | 0.81 | HIF1A (0.46) | — | |
| SCHEMBL11919896 | 0.76 | — | — | |
| SCHEMBL21787568 | 0.76 | — | — | |
| SCHEMBL11271224 | 0.76 | — | — | |
| SCHEMBL7523024 | 0.75 | HIF1A (0.40) | — | |
| SCHEMBL22809886 | 0.74 | CA12 (0.37) | — | |
| SCHEMBL20386016 | 0.74 | CA12 (0.37) | — | |
| SCHEMBL10809579 | 0.73 | HIF1A (0.39) | — | |
| SCHEMBL10808751 | 0.73 | HIF1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120232169-A1 | HIGHLY MONODISPERSE BRANCHED PEG-LIPID CONJUGATES | BIOZONE PHARMACEUTICALS, INC. (US) | 2012-09-13 | — | — | US | claimed |
| WO-2012122144-A1 | HIGHLY MONODISPERSE BRANCHED PEG-LIPID CONJUGATES | WU NIAN (US) | 2012-09-13 | — | — | WO | claimed |
| EP-2673000-B1 | POLYMER-CARBOHYDRATE-LIPID CONJUGATES | WU NIAN (US) | 2018-05-16 | — | — | EP | disclosed |
| US-20100240883-A1 | Lipid-drug conjugates for drug delivery | WU NIAN | 2010-09-23 | — | — | US | disclosed |