Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960583 | 1.00 | TYMP (0.39) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL119773 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL3502363 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL3796623 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL2105114 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL3233362 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL11201526 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL18244171 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL3233355 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD | |
| SCHEMBL21057468 | 0.97 | TYMP (0.41) | TYMPTDP1ALDH1A1CYP3A4ACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | disclosed |