Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 14/20 | 0.65 |
| ▸ | CCR3 | P51677 | 14/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110626 | 1.00 | HRH1 (0.65) | HRH1CCR3KCNH2MEN1KMT2A | |
| SCHEMBL4155971 | 0.89 | CCR3 (0.57) | HRH1CCR3KCNH2MEN1KMT2A | |
| SCHEMBL18841150 | 0.79 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL18841143 | 0.78 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL14110643 | 0.78 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180326 | 0.77 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180245 | 0.76 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL18841157 | 0.76 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL18841145 | 0.75 | HRH1 (0.87) | HRH1CCR3KCNH2 | |
| SCHEMBL180183 | 0.75 | HRH1 (1.00) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100460391-C | Chemical compounds. | ASTRAZENECA AB (SE) | 2009-02-11 | — | — | CN | disclosed |