Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 7/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5015491 | 0.85 | PPARG (0.40) | PPARGOXER1 | |
| SCHEMBL29144774 | 0.78 | IDH1 (0.40) | SMN1; SMN2 | |
| SCHEMBL28341086 | 0.77 | PPARG (0.46) | PPARGOXER1 | |
| SCHEMBL7072559 | 0.77 | KMT2A (0.47) | — | |
| SCHEMBL7952849 | 0.75 | PPARG (0.42) | PPARGOXER1 | |
| SCHEMBL28436072 | 0.75 | PPARG (0.42) | PPARGOXER1 | |
| SCHEMBL4412605 | 0.73 | BCHE (0.39) | — | |
| SCHEMBL670199 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2 | |
| SCHEMBL6472453 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL7551690 | 0.70 | OXER1 (0.59) | PPARGOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107567443-A | biaryl derivatives as GPR120 agonists | 株式会社LG化学 | 2018-01-09 | — | — | CN | disclosed |
| CN-101389628-B | Indolopyridines as EG5 kinesin modulators | 4SC AG | 2013-02-27 | — | — | CN | disclosed |
| CN-101389628-A | Indolopyridines as EG5 kinesin modulators | 4SC AG (DE) | 2009-03-18 | — | — | CN | disclosed |
| CN-101389629-A | Indolopyridines as EG5 kinesin modulators | 4SC AG (DE) | 2009-03-18 | — | — | CN | disclosed |