Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963612 | 0.88 | PLA2G4B (0.60) | PLA2G4BRXRARXRBRXRGNR4A2 | |
| SCHEMBL28814873 | 0.82 | PLA2G4B (0.66) | PLA2G4BTDP1KCNH2PPARDSRD5A2 | |
| SCHEMBL4374627 | 0.76 | NR4A2 (0.71) | PLA2G4BRXRARXRBRXRGNR4A2 | |
| SCHEMBL29223417 | 0.75 | KMT2A (0.51) | PLA2G4BRXRARXRBNR4A2MEN1 | |
| SCHEMBL2957643 | 0.75 | MAPT (0.55) | PLA2G4BMAPTMEN1LMNAKMT2A | |
| SCHEMBL2957648 | 0.74 | MAOB (0.51) | S1PR4PLA2G4BRXRARXRBRXRG | |
| SCHEMBL28571002 | 0.73 | MEN1 (0.50) | S1PR4MAPTMEN1LMNAKMT2A | |
| SCHEMBL4226983 | 0.72 | TTR (0.56) | MAPTKCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL25381694 | 0.72 | KCNH2 (0.62) | KCNH2PPARDALDH1A1 | |
| SCHEMBL27906256 | 0.71 | MRGPRX4 (0.42) | RXRARXRBRXRGMAPTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384592-A | Antiviral compounds | ABBOTT LAB (US) | 2009-03-11 | — | — | CN | disclosed |