Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27960034 | 1.00 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL27754602 | 0.98 | DPP4 (0.96) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL28775288 | 0.92 | DPP4 (1.00) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27754783 | 0.92 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL28775267 | 0.91 | DPP4 (0.98) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL28812915 | 0.90 | DPP4 (1.00) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27755073 | 0.90 | DPP4 (1.00) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL28778774 | 0.89 | DPP4 (0.82) | DPP4DPP8 | |
| Oxalic Acid SCHEMBL27734489 | 0.89 | DPP4 (0.82) | DPP4DPP8 | |
| SCHEMBL27754926 | 0.88 | DPP4 (0.97) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850330-A | Method for preparing N-substituted pyrrolidine derivative through bromination | CHENGDU DIAO PHARMACY GROUP CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-102838589-A | Method for preparing N substituted pyrrolidine derivative through acylation of methyl sulfone chloride | CHENGDU DIAO PHARMACY GROUP CO LTD | 2012-12-26 | — | — | CN | disclosed |
| CN-101397294-B | N-substituted pyrrolidine derivatives and use thereof | CHENGDU DIAO PHARMACY GROUP CO LTD | 2012-12-05 | — | — | CN | disclosed |
| CN-101397294-A | N-substituted pyrrolidine derivatives and use thereof | CHENGDU DIAO PHARMACEUTICAL GR (CN) | 2009-04-01 | — | — | CN | disclosed |