Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802228 | 0.84 | — | — | |
| SCHEMBL1858624 | 0.82 | PTGS1 (0.38) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL9161626 | 0.82 | APP (0.46) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL1979848 | 0.79 | APP (0.48) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL8531226 | 0.78 | APP (0.42) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL25382857 | 0.75 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL5144485 | 0.75 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL17502896 | 0.75 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL25385302 | 0.75 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL15674185 | 0.75 | APP (0.44) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010113183-A2 | PROCESS FOR THE PREPARATION OF 1-[[[3-[2-(DIMETHYLAMINO)ETHYL]-1H-INDOL-5-YL]METHYL]SULFONYL] PYRROLIDINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | MSN LABORATORIES LIMITED (IN) | 2010-10-07 | — | — | WO | claimed |
| WO-2010113183-A2 | PROCESS FOR THE PREPARATION OF 1-[[[3-[2-(DIMETHYLAMINO)ETHYL]-1H-INDOL-5-YL]METHYL]SULFONYL] PYRROLIDINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | MSN LABORATORIES LIMITED (IN) | 2010-10-07 | — | — | WO | disclosed |