Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761337 | 0.98 | KCNH2 (0.51) | HPGDKCNH2HRH3SLC6A2SLC6A4 | |
| SCHEMBL9336823 | 0.93 | KCNH2 (0.52) | HPGDKCNH2HRH3SLC6A2SLC6A4 | |
| SCHEMBL13651792 | 0.89 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3MAPTKDM1A | |
| SCHEMBL19662088 | 0.82 | KCNH2 (0.50) | KCNH2HRH3SMN1; SMN2GAA | |
| SCHEMBL30949069 | 0.78 | HTR2C (0.50) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL20227381 | 0.78 | SLC6A2 (0.44) | KCNH2HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4440921 | 0.78 | HTR2C (0.50) | HPGDALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL8954599 | 0.78 | KCNH2 (0.55) | HPGDKCNH2HRH3ALDH1A1KDM1A | |
| SCHEMBL19126901 | 0.78 | APP (0.51) | KCNH2HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2114351 | 0.77 | KCNH2 (0.44) | HPGDKCNH2HRH3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541768-A | P2X4Receptor antagonists | NIPPON CHEMIPHAR CO (JP) | 2009-09-23 | — | — | CN | disclosed |