Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27760095 | 0.86 | IKBKB (0.35) | CHRM1HRH1PRMT5ACP1IKBKB | |
| SCHEMBL3581077 | 0.83 | MAPK11 (0.47) | CHRM1HRH1ACP1MAPK14MAPK11 | |
| SCHEMBL3581075 | 0.83 | MAPK11 (0.47) | CHRM1HRH1ACP1MAPK14MAPK11 | |
| SCHEMBL20028885 | 0.72 | CHEK1 (0.43) | IKBKBDRD2HTR2AHTR2CKCNH2 | |
| SCHEMBL3577202 | 0.72 | CYP1A2 (0.48) | LMNATSHRNPSR1ALOX15MAPK1 | |
| SCHEMBL3583286 | 0.70 | ACP1 (0.41) | CHRM1HRH1ACP1IKBKBMPO | |
| SCHEMBL3583291 | 0.70 | ACP1 (0.41) | CHRM1HRH1ACP1IKBKBMPO | |
| SCHEMBL27792220 | 0.70 | TSHR (0.40) | CHRM1TSHRHTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4599388 | 0.69 | ACP1 (0.40) | CHRM1HRH1ACP1IKBKBMPO | |
| Azetidine SCHEMBL27976635 | 0.69 | TSHR (0.41) | LMNATSHRHTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101558065-A | Oxazole derivatives as positive allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2009-10-14 | — | — | CN | disclosed |