Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.62 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762719 | 0.87 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL27742036 | 0.85 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL1982602 | 0.84 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL27762662 | 0.84 | TRPV1 (0.56) | TRPV1 | |
| SCHEMBL27742146 | 0.83 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL27762598 | 0.82 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL27762607 | 0.80 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL27742140 | 0.78 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL1982926 | 0.77 | TRPV1 (1.00) | TRPV1 | |
| Acetic Acid SCHEMBL27762599 | 0.76 | TRPV1 (0.93) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102161653-A | Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof | ABBOTT LAB | 2011-08-24 | — | — | CN | claimed |
| CN-101443327-A | Chromanylurea compounds that inhibit vanilloid receptor subtype 1(VR1) receptor and uses thereof | ABBOTT LAB (US) | 2009-05-27 | — | — | CN | claimed |
| CN-102161653-A | Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof | ABBOTT LAB | 2011-08-24 | — | — | CN | disclosed |