Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27807762 | 0.84 | TDP1 (0.41) | TDP1KDM1A | |
| Tert-Butyl Formate SCHEMBL27722913 | 0.83 | TDP1 (0.50) | TDP1KDM1AITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL28050472 | 0.82 | TDP1 (0.45) | TDP1KDM1AITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27702406 | 0.82 | TDP1 (0.48) | TDP1KDM1AITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27721999 | 0.80 | TDP1 (0.46) | TDP1KDM1AITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27591602 | 0.80 | TDP1 (0.46) | TDP1KDM1AITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL28016851 | 0.79 | TDP1 (0.45) | TDP1KDM1AITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL27527154 | 0.79 | TDP1 (0.45) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27663311 | 0.79 | TDP1 (0.45) | TDP1KDM1AITGB3ITGA2B | |
| Tert-Butyl Formate SCHEMBL28007513 | 0.79 | TDP1 (0.45) | TDP1KDM1AITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132954-B | 1,3- benzodioxole derivative | 第三共株式会社 | 2019-01-08 | — | — | CN | disclosed |
| CN-106132954-A | 1,3 benzodioxole derivant | 第三共株式会社 | 2016-11-16 | — | — | CN | disclosed |
| CN-103391936-B | Carcinostatic agent | THE UNIVERSITY OF TOKYO (JP) | 2016-04-27 | — | — | CN | disclosed |
| CN-103391936-A | Anticancer agent | NAT UNIV CORP UNIV TOKYO | 2013-11-13 | — | — | CN | disclosed |
| CN-101679425-B | 6-(pyrrolopyridinyl)-pyrimidine-2-yl-amine and its uses in treating cancer and AIDS | MERCK PATENT GMBH | 2013-11-06 | — | — | CN | disclosed |
| CN-101437829-B | Bisadenosine compounds as adenosine A2A receptor agonists | NOVARTIS AG | 2012-03-21 | — | — | CN | disclosed |
| CN-101679425-A | 6-(pyrrolopyridinyl)-pyrimidine-2-yl-amine derivatives | MERCK PATENT GMBH | 2010-03-24 | — | — | CN | disclosed |
| CN-101522687-A | Heterobicyclic thiophene compounds and methods of use | ARRAY BIOPHARMA INC (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101437829-A | Bisadenosine compounds as adenosine A2A receptor agonists | NOVARTIS AG (CH) | 2009-05-20 | — | — | CN | disclosed |