SCHEMBL2776404

SCHEMBL2776404

CCCCC(Oc1ccccc1)c1ccc(OC)cc1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 7/20 0.53
SLC6A4 P31645 6/20 0.50
SLC6A9 P48067 1/20 0.48
HTR1A P08908 2/20 0.46
SLC6A2 P23975 1/20 0.44
CA4 P22748 1/20 0.44
LTA4H P09960 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27299983 0.89 SLC6A4 (0.62) SLC7A5SLC6A4SLC6A2
SCHEMBL27950265 0.84 SLC7A5 (0.50) SLC7A5SLC6A4LTA4H
SCHEMBL25966679 0.83 CA4 (0.50) SLC7A5SLC6A4SLC6A9HTR1ACA4
SCHEMBL5533459 0.83 SLC7A5 (0.55) SLC7A5SLC6A4SLC6A9HTR1A
SCHEMBL4351195 0.81 SLC6A4 (0.57) SLC7A5SLC6A4SLC6A2
SCHEMBL27980775 0.80 SLC7A5 (0.52) SLC7A5SLC6A4LTA4H
SCHEMBL17278137 0.80 SLC7A5 (0.71) SLC7A5SLC6A4SLC6A9HTR1ASLC6A2
SCHEMBL2774357 0.79 SLC6A4 (0.48) SLC7A5SLC6A4SLC6A9HTR1ASLC6A2
SCHEMBL27980727 0.79 SLC7A5 (0.51) SLC7A5SLC6A4SLC6A2
SCHEMBL27980743 0.79 SLC7A5 (0.51) SLC7A5SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2203412-A1 MONOACYLGLYCEROL LIPASE INHIBITORS FOR MODULATION OF CANNABINOID ACTIVITY NORTHEASTERN UNIVERSITY (US) 2010-07-07 EP disclosed
EP-2203058-A1 METHODS AND COMPOUNDS FOR MODULATING CANNABINOID ACTIVITY NORTHEASTERN UNIVERSITY (US) 2010-07-07 EP disclosed
EP-2051964-A2 FATTY ACID AMIDE HYDROLASE INHIBITORS University of Connecticut (US) 2009-04-29 EP disclosed
WO-2009052320-A1 METHODS AND COMPOUNDS FOR MODULATING CANNABINOID ACTIVITY NORTHEASTERN UNIVERSITY (US) 2009-04-23 WO disclosed
WO-2009052319-A1 MONOACYLGLYCEROL LIPASE INHIBITORS FOR MODULATION OF CANNABINOID ACTIVITY NORTHEASTERN UNIVERSITY (US) 2009-04-23 WO disclosed
WO-2008013963-A2 FATTY ACID AMIDE HYDROLASE INHIBITORS UNIVERSITY OF CONNECTICUT (US) 2008-01-31 WO disclosed