SCHEMBL2776599

SCHEMBL2776599

C[C@H](NC(=O)O)C(=O)N1CCC(Oc2ccc(F)cc2F)CC1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR6 P46095 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2774697 0.89 CCR1 (0.49) GPR6
SCHEMBL2775653 0.86 GPR6 (0.47) GPR6
SCHEMBL2776968 0.84 NAMPT (0.48)
Hydrochloric Acid SCHEMBL2778208 0.83 GPR6 (0.49) GPR6
Hydrochloric Acid SCHEMBL2775952 0.81 DPP4 (0.50) GPR6
SCHEMBL2776203 0.81 CCR1 (0.49) GPR6
SCHEMBL2774650 0.80 GPR6 (0.46) GPR6
SCHEMBL2776919 0.80 CCR1 (0.48) GPR6
SCHEMBL2776625 0.79 NAMPT (0.54)
SCHEMBL2773855 0.79 CCR1 (0.48) GPR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2258697-A1 HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2010-12-08 EP disclosed