Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 7/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13046540 | 0.94 | KCNK3 (0.43) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL13046541 | 0.94 | KCNK3 (0.43) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL2775179 | 0.92 | KCNK3 (0.42) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL2774999 | 0.91 | KCNK3 (0.41) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL2778950 | 0.91 | KCNK3 (0.41) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL1159700 | 0.87 | KCNK3 (0.45) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL31105163 | 0.84 | KCNK3 (0.50) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL2777693 | 0.83 | KCNK3 (0.43) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL13046536 | 0.82 | KCNK3 (0.48) | KCNK3PDE7APDE10APDE3AGAA | |
| SCHEMBL31105340 | 0.81 | KCNK3 (0.61) | KCNK3PDE7APDE10APDE3AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435433-B1 | (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES AS FSH RECEPTOR AGONISTS FOR THE TREATMENT OF FERTILITY DISORDERS | MERCK SHARP & DOHME (NL) | 2013-08-28 | — | — | EP | disclosed |
| US-8071587-B2 | (Dihydro)imidazoiso[5,1-A]quinolines | N. V. ORGANON (NL) | 2011-12-06 | — | — | US | disclosed |
| US-20100324021-A1 | (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES | N.V. ORGANON (NL) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324021-A1 | (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES | NQO2, IPO5, SCN5A | KCNK3 419/4885PDE7A 417/4885PDE10A 919/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.