Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 9/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788862 | 0.80 | BRD4 (0.56) | CDC7JAK2CCNB2CDK1CCNB1 | |
| SCHEMBL27789086 | 0.78 | BRD4 (0.44) | CDC7CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL4342616 | 0.77 | CDC7 (0.61) | CDC7BTKJAK2CCNB2CDK1 | |
| SCHEMBL27767422 | 0.76 | CDC7 (0.47) | CDC7BTKPARP1NPC1RAB9A | |
| SCHEMBL27767424 | 0.76 | IKBKB (0.43) | CDC7JAK2IKBKBPARP1KDM4E | |
| SCHEMBL27788867 | 0.74 | BRD4 (0.40) | CDC7CCNA2CDK2CCNA1PARP1 | |
| SCHEMBL27788861 | 0.74 | BRD4 (0.41) | CDC7CCNA2CDK2CCNA1PARP1 | |
| SCHEMBL2198743 | 0.74 | CDC7 (0.54) | CDC7BTKJAK2CCNB2CDK1 | |
| SCHEMBL27767442 | 0.73 | PARP1 (0.43) | CDC7CCNA2CDK2CCNA1PARP1 | |
| SCHEMBL27767426 | 0.73 | CDC7 (0.43) | CDC7BTKCCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | claimed |
| CN-101622229-A | Novel pyrrole derivatives having ureido group and aminocarbonyl group as substituents | SANTEN PHARMACEUTICAL CO LTD | 2010-01-06 | — | — | CN | claimed |
| CN-101622229-B | Pyrrole derivatives having ureido and aminocarbonyl groups as substituents | SANTEN PHARMACEUTICAL CO LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-101622229-A | Novel pyrrole derivatives having ureido group and aminocarbonyl group as substituents | SANTEN PHARMACEUTICAL CO LTD | 2010-01-06 | — | — | CN | disclosed |