Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | EEF2K | O00418 | 2/20 | 0.36 |
| ▸ | EEF2 | P13639 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60711 | 0.98 | CA1 (0.46) | CA1CA2EEF2KEEF2MEN1 | |
| Bromide SCHEMBL1330860 | 0.93 | CA1 (0.57) | CA1CA2EEF2KEEF2MEN1 | |
| Bromide SCHEMBL1330725 | 0.93 | CA1 (0.57) | CA1CA2EEF2KEEF2MEN1 | |
| Bromide SCHEMBL1330831 | 0.93 | CA1 (0.57) | CA1CA2EEF2KEEF2MEN1 | |
| Bromide SCHEMBL1329494 | 0.93 | CA1 (0.57) | CA1CA2EEF2KEEF2MEN1 | |
| Bromide SCHEMBL711968 | 0.93 | CA1 (0.54) | CA1CA2EEF2KEEF2MEN1 | |
| Boric Acid SCHEMBL2790572 | 0.92 | CA1 (0.46) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL5077157 | 0.92 | CA1 (0.55) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL28416359 | 0.92 | CA1 (0.55) | CA1CA2EEF2KEEF2MEN1 | |
| SCHEMBL5682591 | 0.92 | CA1 (0.55) | CA1CA2EEF2KEEF2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7724433-B2 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-7538933-B2 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20070115550-A1 | Composition for multi-color display material and manufacturing method thereof, and optical device and displaying method thereof | FUJI XEROX CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-20070008439-A1 | Optical composition for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| EP-1734402-A2 | Optical arrangement having a periodic structural body for multi-color display and manufacturing method thereof, and optical element and displaying method thereof | FUJI XEROX CO., LTD. (JP) | 2006-12-20 | — | — | EP | disclosed |