SCHEMBL277678

SCHEMBL277678

CC1CC12CC(=O)NC2=O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
CYP2C19 P33261 1/20 0.43
CYP19A1 P11511 2/20 0.37
CRBN Q96SW2 1/20 0.37
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277991 0.74 CRBN (0.41) TSHRNPSR1KDM4ECYP19A1CRBN
SCHEMBL2546470 0.70 TSHR (0.31) TSHRNPSR1
SCHEMBL83878 0.69
SCHEMBL11757680 0.69 TSHR (0.31) TSHRNPSR1
Hydrogen Sulfide SCHEMBL9272629 0.67 TSHR (0.50) TSHRNPSR1KDM4ELMNACYP2C19
Hydrochloric Acid SCHEMBL5728953 0.67 TSHR (0.50) TSHRNPSR1KDM4ELMNACYP2C19
SCHEMBL926031 0.67 CRBN (0.48) TSHRNPSR1CRBNALDH1A1
SCHEMBL15781887 0.66 CYP2D6 (0.33) CYP2C19
SCHEMBL809281 0.66 CRBN (0.37) TSHRNPSR1CYP19A1CRBN
SCHEMBL10025159 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3518042-B1 SECURITY TONER AND PROCESS OF USING THEREOF XEROX CORP (US) 2023-05-24 EP claimed
US-10705442-B2 Toner compositions with white colorants and processes of making thereof XEROX CORPORATION (US) 2020-07-07 US claimed
US-10642179-B2 Security toner and process using thereof XEROX CORPORATION (US) 2020-05-05 US claimed
EP-3518042-A1 SECURITY TONER AND PROCESS OF USING THEREOF Xerox Corporation (US) 2019-07-31 EP claimed
US-20190227452-A1 SECURITY TONER AND PROCESS OF USING THEREOF U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2019-07-25 US claimed
US-20180173127-A1 TONER COMPOSITIONS WITH WHITE COLORANTS AND PROCESSES OF MAKING THEREOF XEROX CORPORATION 2018-06-21 US claimed
US-20180157187-A1 TONER COMPOSITIONS WITH WHITE COLORANTS AND PROCESSES OF MAKING THEREOF XEROX CORPORATION 2018-06-07 US claimed
US-20180039194-A1 TONER COMPOSITIONS WITH WHITE COLORANTS AND PROCESSES OF MAKING THEREOF XEROX CORPORATION 2018-02-08 US claimed
EP-3279741-A1 TONER COMPOSITIONS WITH WHITE COLORANTS AND PROCESSES OF MAKING THEREOF Xerox Corporation (US) 2018-02-07 EP claimed
US-9562142-B2 Process for crystalline latex production XEROX CORPORATION (US) 2017-02-07 US claimed
EP-2493991-B1 ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS MERCK PATENT GMBH (DE) 2016-03-02 EP claimed
US-9267032-B1 Crystalline polyester latex production by solvent reuse phase inversion emulsification XEROX CORPORATION (US) 2016-02-23 US claimed
US-8551686-B2 Antireflective composition for photoresists AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-10-08 US claimed
EP-2493991-A1 ANTIFEFLECTIVE COMPOSITION FOR PHOTORESISTS AZ Electronic Materials USA Corp. (US) 2012-09-05 EP claimed
WO-2011055209-A1 ANTIFEFLECTIVE COMPOSITION FOR PHOTORESISTS AZ ELECTRONIC MATERIALS USA CORP. (US) 2011-05-12 WO claimed
US-20110104613-A1 Antireflective Composition for Photoresists MERCK PATENT GMBH (DE) 2011-05-05 US claimed
US-7638262-B2 Antireflective composition for photoresists AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-12-29 US claimed
EP-2052293-A2 ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS AZ Electronic Materials USA Corp. (US) 2009-04-29 EP claimed
WO-2008017954-A2 ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-02-14 WO claimed
US-20080038659-A1 Antireflective composition for photoresists MERCK PATENT GMBH (DE) 2008-02-14 US claimed