Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634945 | 0.83 | SMN1; SMN2 (0.41) | CYSLTR2CYSLTR1PTPN11NPSR1SMN1; SMN2 | |
| SCHEMBL4552932 | 0.82 | PDK2 (0.47) | PTPN11PDK2MAPTTP53PTPN1 | |
| SCHEMBL3360791 | 0.78 | PDK2 (0.44) | CYSLTR2CYSLTR1PTPN11NPSR1SMN1; SMN2 | |
| SCHEMBL988298 | 0.77 | PDK2 (0.45) | PTPN11PDK2LMNAMAPTTP53 | |
| SCHEMBL4579086 | 0.77 | PDK2 (0.45) | PTPN11PDK2LMNAMAPTTP53 | |
| SCHEMBL15159993 | 0.76 | MEN1 (0.34) | MEN1KMT2AL3MBTL1MAPTHDAC6 | |
| SCHEMBL28026944 | 0.76 | CYP2C9 (0.46) | CYSLTR2CYSLTR1PTPN11NPSR1MEN1 | |
| SCHEMBL1309247 | 0.76 | PDK2 (0.41) | PTPN11PDK2THRATHRBLMNA | |
| SCHEMBL12578144 | 0.75 | SMN1; SMN2 (0.41) | CYSLTR2CYSLTR1PTPN11NPSR1SMN1; SMN2 | |
| SCHEMBL10429664 | 0.75 | SOAT1 (0.50) | CYSLTR2CYSLTR1PTPN11NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101624441-A | Preparation method and application method of 4-9, 9-diaryl fluorene polymer material containing substituted radical | UNIV NANJING POSTS & TELECOMM | 2010-01-13 | — | — | CN | disclosed |