Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | BUB1 | O43683 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3189576 | 0.88 | PIK3C3 (0.43) | PIK3C3MAPK1JAK2JAK1TYK2 | |
| SCHEMBL1553496 | 0.76 | CNR1 (0.60) | JAK2JAK1TYK2BUB1ABL1 | |
| SCHEMBL1552978 | 0.76 | JAK2 (0.48) | PIK3C3MAPK1JAK2JAK1TYK2 | |
| SCHEMBL1553258 | 0.74 | PIK3CA (0.60) | MAPK1JAK2JAK1TYK2 | |
| SCHEMBL1505591 | 0.74 | NR3C2 (0.56) | MAPK1JAK2JAK1TYK2BUB1 | |
| SCHEMBL20909667 | 0.73 | SMN1; SMN2 (0.68) | JAK2JAK1TYK2 | |
| SCHEMBL1505534 | 0.72 | JAK2 (0.61) | JAK2JAK1TYK2 | |
| SCHEMBL31420515 | 0.72 | JAK2 (0.61) | JAK2JAK1TYK2 | |
| SCHEMBL1553547 | 0.70 | ABL1 (0.58) | ABL1 | |
| SCHEMBL1553602 | 0.70 | NPC1 (0.53) | PIK3C3MAPK1JAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101627038-A | Antibacterial polycyclic urea compounds | ASTRAZENECA AB | 2010-01-13 | — | — | CN | claimed |
| CN-101627038-A | Antibacterial polycyclic urea compounds | ASTRAZENECA AB | 2010-01-13 | — | — | CN | disclosed |