Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789581 | 0.83 | KCNN4 (0.50) | CYP2C9KCNN4ALDH1A1HTTMCOLN3 | |
| SCHEMBL28049560 | 0.80 | CHRM3 (0.46) | CYP2C9KCNN4ALDH1A1CHRM3CHRM2 | |
| SCHEMBL4160700 | 0.74 | KCNN4 (0.37) | CYP2C9KCNN4ALDH1A1HTTMCOLN3 | |
| SCHEMBL29101509 | 0.73 | CYP3A4 (0.41) | CYP2C9KCNN4ALDH1A1KCNE1KCNQ1 | |
| SCHEMBL3818507 | 0.71 | CYP2C9 (0.50) | CYP2C9KCNN4ALDH1A1HTTMCOLN3 | |
| SCHEMBL28743258 | 0.71 | POLB (0.44) | ALDH1A1HTTCHRM3CHRM2CHRM1 | |
| SCHEMBL4160698 | 0.70 | CYP2C9 (0.49) | CYP2C9KCNN4ALDH1A1HTTMCOLN3 | |
| SCHEMBL30097456 | 0.70 | CES1 (0.38) | KCNN4ALDH1A1HTTMCOLN3POLB | |
| Bromomethane SCHEMBL3192554 | 0.68 | CYP2C9 (0.46) | CYP2C9KCNN4ALDH1A1HTTMCOLN3 | |
| SCHEMBL28381845 | 0.68 | KCNN4 (0.41) | KCNN4ALDH1A1KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103497185-A | Pyrazolo(3, 4-B)pyridine derivatives as phosphodiesterase inhibitors | RANBAXY LAB LTD | 2014-01-08 | — | — | CN | disclosed |
| CN-102256963-A | Cyclic pyrimidine-4-carboxamides as CCR2 receptor antagonists for the treatment of inflammation, asthma and COPD | BOEHRINGER INGELHEIM INT | 2011-11-23 | — | — | CN | disclosed |
| CN-101980742-A | Inhaler | VECTURA DELIVERY DEVICES LTD (GB) | 2011-02-23 | — | — | CN | disclosed |
| CN-101801376-A | Pyrazolo (3,4-b) pyridine derivatives as phosphodiesterase inhibitors | RANBAXY LAB LTD | 2010-08-11 | — | — | CN | disclosed |
| CN-101616901-A | Inhibitors of phosphodiesterase type IV | RANBAXY LAB LTD | 2009-12-30 | — | — | CN | disclosed |