Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 8/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27790110 | 0.90 | PPARD (0.43) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL27790208 | 0.90 | PPARD (0.45) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL27790117 | 0.90 | PPARD (0.40) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL27768758 | 0.89 | PPARD (0.39) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL27790111 | 0.89 | PPARD (0.40) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL27790112 | 0.87 | PPARD (0.38) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL27768616 | 0.82 | PPARD (0.33) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL27790115 | 0.81 | PPARD (0.39) | PPARDFFAR1PPARGPPARACHRM5 | |
| SCHEMBL5433317 | 0.81 | PPARD (0.41) | PPARDFFAR1PPARGPPARAALOX5 | |
| SCHEMBL3538554 | 0.81 | PPARD (0.39) | PPARDFFAR1PPARGPPARACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100582104-C | Oxadiazolone derivatives as PPAR delta agonists | SANOFI AVENTIS DEUTSCHLAND | 2010-01-20 | — | — | CN | disclosed |