Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | FYN | P06241 | 2/20 | 0.51 |
| ▸ | HCK | P08631 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | JAK3 | P52333 | 2/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | YES1 | P07947 | 1/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | FGR | P09769 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772685 | 0.89 | LCK (0.72) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL27768701 | 0.88 | LCK (0.55) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL19390084 | 0.84 | LCK (0.61) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL27747467 | 0.83 | LCK (0.55) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL27582872 | 0.83 | MAPK14 (0.57) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL27684282 | 0.81 | LCK (0.56) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL27582904 | 0.81 | MAPK14 (0.58) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL27562382 | 0.80 | MAPK14 (0.72) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL28781351 | 0.80 | LCK (0.52) | LCKMAPK14MAPK13EGFRFYN | |
| SCHEMBL27655074 | 0.79 | MAPK14 (0.50) | LCKMAPK14MAPK13EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101481359-A | Cyclic protein tyrosine kinase inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-07-15 | — | — | CN | claimed |