Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.74 |
| ▸ | CCR6 | P51684 | 1/20 | 0.73 |
| ▸ | CXCR1 | P25024 | 5/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13197595 | 0.88 | CXCR2 (0.76) | CXCR2CCR6CXCR1 | |
| SCHEMBL14310580 | 0.87 | CXCR2 (0.76) | CXCR2CCR6CXCR1 | |
| SCHEMBL12087249 | 0.86 | CXCR2 (0.70) | CXCR2CCR6CXCR1 | |
| SCHEMBL13197558 | 0.86 | CXCR2 (0.69) | CXCR2CCR6CXCR1 | |
| SCHEMBL12570024 | 0.85 | CXCR2 (1.00) | CXCR2CCR6CXCR1 | |
| SCHEMBL12086722 | 0.85 | CXCR2 (1.00) | CXCR2CCR6CXCR1 | |
| SCHEMBL12741331 | 0.85 | CXCR2 (0.72) | CXCR2CCR6CXCR1 | |
| SCHEMBL12262520 | 0.84 | CXCR2 (0.93) | CXCR2CCR6CXCR1 | |
| SCHEMBL12087137 | 0.84 | CXCR2 (1.00) | CXCR2CCR6CXCR1 | |
| SCHEMBL14450094 | 0.84 | CXCR2 (0.78) | CXCR2CCR6CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091543-A1 | NOVEL HYDRAZINO-CYCLOBUT-3-ENE-1, 2-DIONE DERIVATIVES AS CXCR2 ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2010-08-19 | — | — | WO | disclosed |
| WO-2010091543-A1 | NOVEL HYDRAZINO-CYCLOBUT-3-ENE-1, 2-DIONE DERIVATIVES AS CXCR2 ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2010-08-19 | — | — | WO | disclosed |