Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.62 |
| ▸ | GSK3A | P49840 | 1/20 | 0.62 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481892 | 0.85 | MTOR (0.69) | MTORPIK3CAGSK3A | |
| SCHEMBL481734 | 0.81 | MTOR (0.72) | MTORPIK3CAGSK3A | |
| SCHEMBL481800 | 0.80 | MTOR (0.80) | MTORPIK3CAGSK3AMAP3K11 | |
| SCHEMBL481530 | 0.79 | MTOR (0.69) | MTORPIK3CAGSK3A | |
| SCHEMBL481890 | 0.79 | MTOR (0.71) | MTORPIK3CAGSK3A | |
| SCHEMBL482293 | 0.78 | MTOR (0.75) | MTORPIK3CAGSK3A | |
| SCHEMBL8516387 | 0.78 | MTOR (0.71) | MTORPIK3CAGSK3A | |
| SCHEMBL481513 | 0.78 | MTOR (0.75) | MTORPIK3CAGSK3A | |
| SCHEMBL481552 | 0.78 | MTOR (1.00) | MTORPIK3CAGSK3A | |
| SCHEMBL481693 | 0.77 | MTOR (1.00) | MTORPIK3CAGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101573360-A | Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors | SIGNAL PHARM LLC (US) | 2009-11-04 | — | — | CN | disclosed |