Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1957379 | 0.96 | BCL2 (0.80) | BCL2 | |
| SCHEMBL2481508 | 0.90 | BCL2 (0.73) | BCL2 | |
| SCHEMBL2777043 | 0.90 | BCL2 (0.88) | BCL2 | |
| SCHEMBL15991888 | 0.89 | BCL2 (0.82) | BCL2 | |
| SCHEMBL3496249 | 0.88 | BCL2 (0.75) | BCL2 | |
| SCHEMBL2480390 | 0.88 | BCL2 (0.75) | BCL2 | |
| SCHEMBL1957674 | 0.88 | BCL2 (0.83) | BCL2 | |
| SCHEMBL1957091 | 0.88 | BCL2 (0.82) | BCL2 | |
| SCHEMBL23165076 | 0.87 | BCL2 (0.64) | BCL2 | |
| SCHEMBL2774580 | 0.87 | BCL2 (0.89) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065824-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | disclosed |