Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770493 | 1.00 | MAPT (0.49) | MAPTPTGER1LMNANPSR1RORC | |
| SCHEMBL15663411 | 0.93 | PTGER1 (0.54) | MAPTPTGER1LMNANPSR1RORC | |
| SCHEMBL2174925 | 0.90 | PTGER1 (0.53) | MAPTPTGER1LMNANPSR1RORC | |
| SCHEMBL2174921 | 0.90 | PTGER1 (0.53) | MAPTPTGER1LMNANPSR1RORC | |
| SCHEMBL27770491 | 0.87 | MAPT (0.52) | MAPTPTGER1LMNANPSR1RORC | |
| SCHEMBL27770492 | 0.86 | MAPT (0.53) | MAPTPTGER1LMNANPSR1RORC | |
| SCHEMBL2176549 | 0.83 | PTGER1 (0.61) | PTGER1LMNARORCALDH1A1SMN1; SMN2 | |
| SCHEMBL2176553 | 0.83 | PTGER1 (0.61) | PTGER1LMNARORCALDH1A1SMN1; SMN2 | |
| SCHEMBL2173616 | 0.80 | PTGER1 (0.55) | PTGER1LMNAKMT2AMEN1THRB | |
| SCHEMBL2175487 | 0.80 | PTGER1 (0.59) | PTGER1LMNARORCALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | claimed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | claimed |
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | disclosed |