Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.63 |
| ▸ | ACR | P10323 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12520418 | 0.91 | PRSS1 (0.73) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL16838267 | 0.86 | MAPT (0.72) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL29749397 | 0.85 | PRSS1 (0.66) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL1671519 | 0.85 | PRSS1 (0.66) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL28083375 | 0.84 | PRSS1 (0.65) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL8210665 | 0.84 | PRSS1 (0.65) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL11283261 | 0.84 | PRSS1 (0.65) | PRSS1ACRMAPTKMT2AMEN1 | |
| SCHEMBL21159215 | 0.84 | KMT2A (0.67) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL31321689 | 0.83 | PRSS1 (0.63) | PRSS1ACRMAPTKMT2AL3MBTL1 | |
| SCHEMBL31321629 | 0.83 | PRSS1 (0.63) | PRSS1ACRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |