Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.73 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941622 | 0.88 | SRD5A2 (0.81) | SRD5A2CES2CNR1CNR2MEN1 | |
| SCHEMBL1237189 | 0.88 | SRD5A2 (0.79) | SRD5A2CES2CNR1CNR2MEN1 | |
| SCHEMBL1044812 | 0.86 | SRD5A2 (0.83) | SRD5A2CES2CNR1CNR2LMNA | |
| SCHEMBL7486845 | 0.85 | SRD5A2 (0.76) | SRD5A2CES2CNR1CNR2MEN1 | |
| SCHEMBL4979512 | 0.83 | SRD5A2 (0.73) | SRD5A2CES2CNR1CNR2MEN1 | |
| SCHEMBL28565479 | 0.83 | SRD5A2 (0.73) | SRD5A2CES2CNR1CNR2MEN1 | |
| SCHEMBL17894214 | 0.83 | SRD5A2 (0.73) | SRD5A2CES2CNR1CNR2MEN1 | |
| SCHEMBL8642093 | 0.82 | SRD5A2 (0.68) | SRD5A2CES2CNR2MEN1KMT2A | |
| Propene SCHEMBL28144333 | 0.81 | SRD5A2 (0.69) | SRD5A2CES2CNR1CNR2MEN1 | |
| SCHEMBL5687867 | 0.80 | SRD5A2 (0.69) | SRD5A2CES2CNR1CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489555-A | Nf-kappa | OTSUKA PHARMA CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |