Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 16/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 15/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771680 | 1.00 | DPP4 (0.46) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL294870 | 0.76 | DPP4 (0.54) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL294679 | 0.66 | DPP4 (0.68) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL295145 | 0.64 | DPP4 (0.75) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL294346 | 0.64 | DPP4 (1.00) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL294237 | 0.63 | DPP4 (0.67) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL4404901 | 0.62 | DPP4 (0.43) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703689 | 0.62 | DPP4 (0.57) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2703685 | 0.62 | DPP4 (0.57) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL294677 | 0.62 | DPP4 (0.69) | DPP4DPP8DPP9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101595109-A | 7, 8-dihydro-1, 6-naphthyridin-5 (6H) -ones and related bicyclic compounds as dipeptidyl peptidase IV inhibitors and methods | BRISTOL MYERS SQUIBB CO (US) | 2009-12-02 | — | — | CN | disclosed |