Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3165167 | 0.79 | PTGDR2 (0.44) | PTGDR2 | |
| SCHEMBL3164798 | 0.75 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL27792895 | 0.75 | PTGDR2 (0.44) | PTGDR2POLBKDM4E | |
| SCHEMBL3159520 | 0.74 | PTGDR2 (0.46) | PTGDR2KDM4E | |
| SCHEMBL3168468 | 0.74 | PTGDR2 (0.57) | PTGDR2 | |
| SCHEMBL3166129 | 0.74 | PTGDR2 (0.44) | PTGDR2 | |
| SCHEMBL3168073 | 0.74 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL3176967 | 0.72 | PTGDR2 (0.51) | PTGDR2HTR6 | |
| SCHEMBL3165962 | 0.71 | PTGDR2 (0.52) | PTGDR2HTR6CREBBPKDM4E | |
| SCHEMBL3165853 | 0.71 | PTGDR2 (0.55) | PTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |