Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26095809 | 0.70 | CXCR2 (0.35) | CXCR2 | |
| SCHEMBL26092903 | 0.70 | CXCR2 (0.33) | CXCR2 | |
| SCHEMBL26092908 | 0.70 | CXCR2 (0.33) | CXCR2 | |
| SCHEMBL26095807 | 0.70 | CXCR2 (0.35) | CXCR2 | |
| SCHEMBL26094551 | 0.70 | CXCR2 (0.33) | CXCR2 | |
| SCHEMBL26095688 | 0.68 | CXCR2 (0.32) | CXCR2 | |
| SCHEMBL26095691 | 0.68 | CXCR2 (0.32) | CXCR2 | |
| SCHEMBL7297728 | 0.67 | — | — | |
| SCHEMBL6763820 | 0.66 | GAA (0.44) | ALDH1A1ADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL10081304 | 0.65 | CXCR4 (0.55) | ADRA2AADRA2BADRA2CLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522678-A | Novel imidazolinone derivatives, their preparation as medicaments, pharmaceutical compositions, their use as inhibitors of kinases, in particular CDC7 | SANOFI AVENTIS (FR) | 2009-09-02 | — | — | CN | disclosed |