SCHEMBL2777609

SCHEMBL2777609

C[C@@H](C(=O)Oc1ccccc1)N(O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 3/20 0.50
▸ ATM Q13315 2/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.44
▸ MEN1 O00255 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ LMNA P02545 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ GAA P10253 1/20 0.41
▸ MTNR1A P48039 3/20 0.41
▸ MTNR1B P49286 3/20 0.41
▸ NPY5R Q15761 1/20 0.41
▸ SLC1A3 P43003 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ GFER P55789 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231429 0.85 ATM (0.50) ELANEATML3MBTL1TDP1MEN1
SCHEMBL3876427 0.83 ELANE (0.49) ELANEATML3MBTL1TDP1MEN1
SCHEMBL21276510 0.80 ELANE (0.53) ELANEATML3MBTL1TDP1MEN1
SCHEMBL2459478 0.79 ELANE (0.56) ELANEATML3MBTL1TDP1MEN1
SCHEMBL29187166 0.79 ELANE (0.72) ELANEATML3MBTL1TDP1MEN1
SCHEMBL514357 0.79 ELANE (0.72) ELANEATML3MBTL1TDP1MEN1
SCHEMBL26918592 0.79 ATM (0.45) ELANEATML3MBTL1TDP1MEN1
Hydrochloric Acid SCHEMBL25243908 0.78 ELANE (0.70) ELANEATML3MBTL1TDP1MEN1
SCHEMBL3740302 0.78 ELANE (0.55) ELANEATML3MBTL1TDP1MEN1
SCHEMBL15064173 0.78 ELANE (0.55) ELANEATML3MBTL1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004058210-A1 COSMETIC COMPOSITION CONTAINING A MELANIN PRECURSOR UNILEVER PLC (GB) 2004-07-15 — — WO claimed
CN-106266587-B orchid extract and preparation method and application thereof 青山兰花生物科技有限公司 2019-11-29 — — CN disclosed
CN-109475505-A Peroral dosage form with pharmaceutical compositions, barrier layer and medicine layer 度瑞公司 2019-03-15 — — CN disclosed
EP-2064251-B1 BIOMIMETIC COMPOUNDS AND SYNTHETIC METHODS THEREFOR KENSEY NASH CORP (US) 2017-10-25 — — EP disclosed
CN-106309262-A Phalaenopsis amabilis extract for whitening skin and resisting skin aging 上海奇易化妆品有限公司 2017-01-11 — — CN disclosed
CN-106266587-A Orchid extract and preparation method and application thereof 青山兰花生物科技有限公司 2017-01-04 — — CN disclosed
CN-106137816-A A herba Basellae Rubrae extract and its application 徐慧妤 2016-11-23 — — CN disclosed
US-8815793-B2 Polymeric compositions and related methods of use NORTHWESTERN UNIVERSITY (US) 2014-08-26 — — US disclosed
US-8575276-B2 Biomimetic compounds and synthetic methods therefor KNC NER ACQUISITION SUB, INC. (US) 2013-11-05 — — US disclosed
CN-101198309-B Use of hair protection composition in preparing hair protection agent ASAHI KASEI CHEMICALS CORP (JP) 2012-11-07 — — CN disclosed
EP-1735456-A2 POLYMERIC COMPOSITIONS AND RELATED METHODS OF USE Northwestern University (US) 2006-12-27 — — EP disclosed
WO-2006091226-A2 POLYMERIC COMPOSITIONS AND RELATED METHODS OF USE NORTHWESTERN UNIVERSITY (US) 2006-08-31 — — WO disclosed
CN-1803124-A Gamma-polyglutamic acid, gamma-polyglutamate and application of hydrogel thereof EAST SEA BIOTECHNOLOGY CO LTD (CN) 2006-07-19 — — CN disclosed
US-20060009550-A1 Polymeric compositions and related methods of use NIH - DEITR 2006-01-12 — — US disclosed
US-20050288398-A1 Polymeric compositions and related methods of use NIH - DEITR 2005-12-29 — — US disclosed
WO-2005118831-A2 POLYMERIC COMPOSITIONS AND RELATED METHODS OF USE NORTHWESTERN UNIVERSITY (US) 2005-12-15 — — WO disclosed
CN-1217644-C Beauty and skin composition containing plant extract OREAL (FR) 2005-09-07 — — CN disclosed
US-20040018259-A1 Use of at least one extract of a plant of the genus lannea in a cosmetic or dermopharmaceutical composition PAULY GILLES (FR) 2004-01-29 — — US disclosed
US-6599537-B1 Antiradical, cytophotoprotective, tyrosinase and melanogenesis inhibiting and antiprotease effects COGNIS FRANCE S.A. (FR) 2003-07-29 — — US disclosed
CN-1261528-A Beauty and skin composition containing plant extract OREAL (FR) 2000-08-02 — — CN disclosed
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