⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150133 | 0.72 | — | — | |
| SCHEMBL9533544 | 0.67 | TTR (0.33) | — | |
| SCHEMBL392588 | 0.60 | — | — | |
| SCHEMBL1458170 | 0.56 | — | — | |
| SCHEMBL8984230 | 0.56 | TTR (0.53) | — | |
| SCHEMBL232809 | 0.55 | — | — | |
| SCHEMBL1490317 | 0.55 | — | — | |
| SCHEMBL6716929 | 0.53 | — | — | |
| SCHEMBL232211 | 0.53 | — | — | |
| SCHEMBL13836465 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987373-A | Radiation protection hydrogel and preparation method and application thereof | 赛克赛斯生物科技股份有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | claimed |
| EP-3107542-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | Aerpio Therapeutics, Inc. (US) | 2016-12-28 | — | — | EP | claimed |
| CN-106232120-A | The method preparing N benzyl 3 hydroxyl 4 substituted pyridine 2 (1H) ketone | 爱尔皮奥治疗有限公司 | 2016-12-14 | — | — | CN | claimed |
| US-9388135-B2 | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2-(1H)-ones | AERPIO THERAPEUTICS, INC. (US) | 2016-07-12 | — | — | US | claimed |
| WO-2015126860-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | AERPIO THERAPEUTICS, INC. (US) | 2015-08-27 | — | — | WO | claimed |
| US-20150232425-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | AERPIO THERAPEUTICS, INC. | 2015-08-20 | — | — | US | claimed |
| US-8975259-B2 | Compositions and methods for inhibiting G protein signaling | UNIVERSITY OF ROCHESTER (US) | 2015-03-10 | — | — | US | claimed |
| US-20100130505-A1 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2010-05-27 | — | — | US | claimed |
| EP-2147310-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | University of Rochester (US) | 2010-01-27 | — | — | EP | claimed |
| WO-2009020677-A9 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIV ROCHESTER (US) | 2009-04-16 | — | — | WO | claimed |
| WO-2009020677-A2 | COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING | UNIVERSITY OF ROCHESTER (US) | 2009-02-12 | — | — | WO | claimed |
| EP-1287833-B1 | Liposome containing hydrophobic iodine compound and X-ray contrast medium comprising said liposome | FUJIFILM CORP (JP) | 2007-10-10 | — | — | EP | claimed |
| US-7008614-B2 | Liposome containing hydrophobic iodine compound and X-ray contrast medium for radiograph comprising the liposome | FUJI PHOTO FILM CO., LTD. (JP) | 2006-03-07 | — | — | US | claimed |
| US-20030086875-A1 | Liposome containing hydrophobic iodine compound and X-ray contrast medium for radiograph comprising the liposome | FUJI PHOTO FILM CO., LTD. | 2003-05-08 | — | — | US | claimed |
| EP-1287833-A2 | Liposome containing hydrophobic iodine compound and X-ray contrast medium comprising said liposome | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-05 | — | — | EP | claimed |
| EP-0549600-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1993-07-07 | — | — | EP | claimed |
| WO-1992005163-A1 | 5-TRIFLUOROACYLAMINO-2-ARYL OXAZOLES | PFIZER INC. (US) | 1992-04-02 | — | — | WO | claimed |
| CN-116987373-A | Radiation protection hydrogel and preparation method and application thereof | 赛克赛斯生物科技股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| US-4876127-A | ARYL PHOSPHORYL AZIDE | ALLIED-SIGNAL INC. (US) | 1989-10-24 | — | — | US | disclosed |