Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 3/20 | 0.73 |
| ▸ | RORC | P51449 | 3/20 | 0.73 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.73 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.73 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.73 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.71 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.63 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.63 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.63 |
| ▸ | POLA1 | P09884 | 1/20 | 0.62 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cholesterol SCHEMBL150062 | 1.00 | OSBP (0.73) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL4786128 | 1.00 | OSBP (0.73) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL27962121 | 1.00 | OSBP (0.73) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL29729264 | 1.00 | OSBP (0.73) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL28637815 | 1.00 | OSBP (0.73) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL28494148 | 0.99 | OSBP (0.72) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL27761732 | 0.98 | OSBP (0.71) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL3267892 | 0.98 | OSBP (0.71) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL3267895 | 0.98 | OSBP (0.71) | OSBPRORCUSP2LMNAABCB1 | |
| Cholesterol SCHEMBL28929518 | 0.98 | OSBP (0.73) | OSBPRORCUSP2LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108024957-B | Compositions and methods for nanoparticle lyophilisate form | 日东电工株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-111386105-A | Membrane fusion compounds for delivery of bioactive molecules | 日东电工株式会社 | 2020-07-07 | — | — | CN | disclosed |
| CN-111214701-A | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2020-06-02 | — | — | CN | disclosed |
| CN-106573133-B | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2020-03-03 | — | — | CN | disclosed |
| CN-108096192-A | Proliposome testosterone preparation | 健康科学西部大学 | 2018-06-01 | — | — | CN | disclosed |
| CN-104780914-B | Proliposomal testosterone formulations | 健康科学西部大学 | 2018-02-09 | — | — | CN | disclosed |
| CN-104780914-A | Proliposomal testosterone formulations | UNIV WESTERN HEALTH SCIENCES | 2015-07-15 | — | — | CN | disclosed |
| CN-104382853-A | Processes and Compositions for Liposomal and Efficient Delivery of Gene Silencing Therapeutics | MARINA BIOTECH INC | 2015-03-04 | — | — | CN | disclosed |
| CN-102231979-B | Liposome efficient delivery methods and compositions for gene silencing therapeutics | MARINA BIOTECH, INC. (US) | 2014-10-29 | — | — | CN | disclosed |
| CN-101674853-B | Amino acid lipids and uses thereof | NASTECH PHARM CO | 2013-03-27 | — | — | CN | disclosed |
| CN-102231979-A | Liposome efficient delivery methods and compositions for gene silencing therapeutics | MDRNA INC | 2011-11-02 | — | — | CN | disclosed |
| CN-101674853-A | Amino acid lipids and uses thereof | NASTECH PHARM CO | 2010-03-17 | — | — | CN | disclosed |