Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673892 | 0.83 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL15727117 | 0.77 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL5673071 | 0.73 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL5673209 | 0.73 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL15727101 | 0.73 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL14035560 | 0.72 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL3528076 | 0.71 | NEU3 (0.58) | — | |
| SCHEMBL5673213 | 0.71 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL73063 | 0.71 | HDAC3 (0.61) | — | |
| SCHEMBL13719801 | 0.71 | TRPV1 (0.46) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100537528-C | 4-(methyl sulfonyl amino) phenyl analogues as vanilloid antagonist showing excellent analgesic activity and the pharmaceutical compositions comprising the same | GRUENENTHAL GMBH (DE) | 2009-09-09 | — | — | CN | disclosed |