Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 18/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27779312 | 1.00 | CHRM3 (0.57) | CHRM3CHRM2CHRM1HRH1 | |
| SCHEMBL4891590 | 0.91 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4887549 | 0.91 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4897583 | 0.89 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4893920 | 0.86 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4916264 | 0.85 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4892149 | 0.85 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4892142 | 0.85 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4884993 | 0.84 | CHRM3 (0.57) | CHRM3CHRM2CHRM1 | |
| SCHEMBL15005403 | 0.84 | CHRM3 (0.53) | CHRM3CHRM2CHRM1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101663270-A | Quaternary ammonium compounds useful as muscarinic receptor antagonists | THERAVANCE INC | 2010-03-03 | — | — | CN | disclosed |