Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | MMP9 | P14780 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 12/20 | 0.58 |
| ▸ | CA2 | P00918 | 12/20 | 0.58 |
| ▸ | CA9 | Q16790 | 9/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002519 | 0.97 | TSHR (0.74) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL372403 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL28151887 | 0.95 | TSHR (0.70) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL28832743 | 0.95 | TSHR (0.70) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| Fluoride SCHEMBL28098238 | 0.95 | TSHR (0.70) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL27903035 | 0.95 | TSHR (0.70) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL28587280 | 0.90 | TSHR (0.71) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| Methanesulfonic Acid Dodecyl Ester SCHEMBL27884495 | 0.90 | TSHR (0.71) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| Benzene SCHEMBL27904966 | 0.90 | TSHR (0.64) | TSHRUSP2ALDH1A1KDM4ELMNA | |
| SCHEMBL875919 | 0.90 | TSHR (0.79) | TSHRUSP2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101641345-A | Crystalline and amorphous imatinib base, imatinib mesylate and methods of making the same | SICOR INC US | 2010-02-03 | — | — | CN | disclosed |