Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 8/20 | 0.48 |
| ▸ | CA2 | P00918 | 8/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1563800 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| SCHEMBL226823 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| SCHEMBL4961531 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| SCHEMBL9269549 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| SCHEMBL4957711 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| SCHEMBL4959131 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| Zinc Ion SCHEMBL205290 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| SCHEMBL9120608 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| Potassium Ion SCHEMBL5888927 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT | |
| SCHEMBL9316627 | 0.95 | HDAC1 (0.57) | HDAC1SRD5A2MEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440263-B | Method for preparing p-tert-butyl benzaldehyde by liquid-phase oxidation of p-tert-butyl toluene | 南京大学盐城环保技术与工程研究院 | 2021-09-28 | — | — | CN | disclosed |
| CN-109354712-A | A kind of nucleating agent compositions and application thereof for improving polypropylene rigidity and lowering polypropylene mist degree | 山西省化工研究所（有限公司） | 2019-02-19 | — | — | CN | disclosed |
| EP-2554586-B1 | GRANULATED RESIN ADDITIVE COMPOSITION | ADEKA CORP (JP) | 2017-09-06 | — | — | EP | disclosed |
| US-9527981-B2 | Granulated resin additive composition | ADEKA CORPORATION (JP) | 2016-12-27 | — | — | US | disclosed |
| US-9441091-B2 | Transparentization agent composition containing sorbitol compound and method for producing polypropylene resin composition using this sorbitol compound | ADEKA CORPORATION (JP) | 2016-09-13 | — | — | US | disclosed |
| EP-2492308-B1 | POLYOLEFIN RESIN COMPOSITION | ADEKA CORP (JP) | 2015-10-21 | — | — | EP | disclosed |
| EP-2639266-B1 | POLYPROPYLENE RESIN COMPOSITION | ADEKA CORP (JP) | 2015-03-18 | — | — | EP | disclosed |
| EP-2554591-B1 | TRANSPARENTIZATION AGENT COMPOSITION CONTAINING SORBITOL COMPOUND AND METHOD FOR PRODUCING POLYPROPYLENE RESIN COMPOSITION USING THIS SORBITOL COMPOUND | ADEKA CORP (JP) | 2014-12-24 | — | — | EP | disclosed |
| US-20140128520-A1 | TRANSPARENTIZATION AGENT COMPOSITION CONTAINING SORBITOL COMPOUND AND METHOD FOR PRODUCING POLYPROPYLENE RESIN COMPOSITION USING THIS SORBITOL COMPOUND | ADEKA CORPORATION (JP) | 2014-05-08 | — | — | US | disclosed |
| EP-2639266-A1 | POLYPROPYLENE RESIN COMPOSITION | Adeka Corporation (JP) | 2013-09-18 | — | — | EP | disclosed |
| EP-2554591-A1 | TRANSPARENTIZATION AGENT COMPOSITION CONTAINING SORBITOL COMPOUND AND METHOD FOR PRODUCING POLYPROPYLENE RESIN COMPOSITION USING THIS SORBITOL COMPOUND | Adeka Corporation (JP) | 2013-02-06 | — | — | EP | disclosed |
| EP-2554586-A1 | GRANULATED RESIN ADDITIVE COMPOSITION | Adeka Corporation (JP) | 2013-02-06 | — | — | EP | disclosed |
| US-20130012630-A1 | GRANULATED RESIN ADDITIVE COMPOSITION | ADEKA CORPORATION (JP) | 2013-01-10 | — | — | US | disclosed |
| US-20120296018-A1 | TRANSPARENTIZATION AGENT COMPOSITION CONTAINING SORBITOL COMPOUND AND METHOD FOR PRODUCING POLYPROPYLENE RESIN COMPOSITION USING THIS SORBITOL COMPOUND | ADEKA CORPORATION (JP) | 2012-11-22 | — | — | US | disclosed |
| EP-2492308-A1 | POLYOLEFIN RESIN COMPOSITION | Adeka Corporation (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120178861-A1 | POLYOLEFIN RESIN COMPOSITION | ADEKA CORPORATION (JP) | 2012-07-12 | — | — | US | disclosed |
| US-20100204374-A1 | NUCLEATING AGENT MASTERBATCH FOR POLYOLEFIN RESIN | ADEKA CORPORATION (JP) | 2010-08-12 | — | — | US | disclosed |
| EP-2192147-A1 | NUCLEATOR MASTERBATCH FOR POLYOLEFIN RESIN | Adeka Corporation (JP) | 2010-06-02 | — | — | EP | disclosed |
| EP-1209190-B1 | NUCLEATING AGENT | ASAHI DENKA KOGYO KK (JP) | 2006-03-29 | — | — | EP | disclosed |
| EP-1209190-A1 | NUCLEATING AGENT | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 2002-05-29 | — | — | EP | disclosed |